WS2: BioNetVisA: from biological network reconstruction to data visualization and analysis in molecular biology and medicine


Emmanuel Barillot, Inna Kuperstein, Andrei Zinovyev (Institut Curie - INSERM / Mines ParisTech, Paris, France)
Hiroaki Kitano (Okinawa Institute of Science and Technology Graduate University (OIST) and RIKEN Center for Integrative Medical Sciences, Japan)
Samik Ghosh (Systems Biology Institute, Tokyo, Japan)
Robin Haw (Ontario Institute for Cancer Research, Toronto, Ontario, Canada)
Alfonso Valencia (Spanish National Bioinformatics Institute, Madrid, Spain)
Nicolas Le Novère (Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom)
Minoru Kanehisa (Institute for Chemical Research, Kyoto University)
Lodewyk Wessels (Computational Cancer Biology, NKI, Amsterdam)
Patrick Kemmeren (Princess Maxima Center for Pediatric Oncology, Utrecht)

Abstract submission site and workshop program

Abstract submission deadline: closed

Workshop Summary:

Today's biology is largely data-driven, thanks to high-throughput technologies that allow investigating molecular and cellular aspects of life on large scales. These technologies comprise, for instance, microarrays, nextgeneration sequencers, mass spectrometers, or interaction screens. Making biological sense out of the amount of produced data requires their interpretation in the context of biomolecular networks that govern cellular and physiological processes. In parallel to this technological revolution, the last decades have seen the accumulation of considerable knowledge about those processes and their role in the health and diseases. In many cases, the mechanism of molecular interaction has been experimentally elucidated. A large part of this information is available in the scientific literature and is also being integrated into network databases by scientists and curators. Matching network database evolution to highthroughput data analysis faces the challenge of discrepancy between ever faster and cheaper data production versus the long and costly process of database construction and maintenance. A consequence is the development of a vibrant field of biological network reconstruction, visualization, analysis and modeling, which constitutes the motivation of the BioNetVisA workshop.

The goal of BioNetVisA workshop is to bring together the different actors of network biology, whether database providers, experimental biologists and clinicians involved in systems biology approaches, as well as computational biologists involved in data analysis and modeling. The participants will be exposed to the different paradigms of network biology and the latest achievements in the field. The BioNetVisA workshop also aims at identifying bottlenecks and proposing short- and long-term objectives for the community as discussing questions about accessibility of available tools for wide range of user in every-day standalone application in biological and clinical labs. In addition, the possibilities for collective efforts and future development directions will be discussed during the round table panel.

Target Audience
The workshop targets computational systems biologists, molecular and cell biologists, clinicians and a wide audience interested in update and discussion around current status of network biology, pathway databases, and related analysis tools, including visualization, statistical analysis and dynamic modelling. No computational background is required to attend the workshop. The round table panel planned at the end of the workshop will be a forum for live discussion around those topics.

Keynote speakers:

Minoru Kanehisa (Institute for Chemical Research, Kyoto University)
Alfonso Valencia (Spanish National Bioinformatics Institute, Madrid, Spain)

Invited speakers:

Stephan Gebel (University of Luxembourg, Luxembourg)
Ronan Fleming (University of Luxembourg, Luxembourg)
Andrei Zinovyev (Institut Curie, Paris, France)
Ugur Dogrusoz (Bilkent University, Ankara, Turkey)
Mark Ibberson (Swiss Institute of Bioinformatics, Lausanne, Switzerland)
Barry Hardy (Douglas Connect GmbH, Basel, Switzerland)
Gregory Batt (Institut Pasteur, Paris, France)
Patrick Kemmeren (Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands)

Workshop Agenda:

Tuesday, September 12, 2017
Venue: Kollegienhaus, University of Basel

9:00 – 10:40 Session I: Signalling and metabolic network databases
10:40 – 11:05 Coffee break
11:05 – 12:30 Session II: Platforms and method for analysis of complex biological networks
12:30 – 13:30 Lunch break
13:30 – 15:00 Session III: Biological networks in drug discovery and toxicology studies
15:00 – 15:30 Coffee break
15:30 – 17:00 Session IV: Biological networks modelling in medicine

See more information on the workshop website.